Systematic Review: Culturally Tailored Digital Substance Use Prevention Interventions for Black Adolescents
Kammarauche Aneni, Destiny Pegram, Jenny Meyer, Melissa C. Funaro, Roberta L. Bruhn, Uzochukwu Imo, Aaron Hogue, José Szapocznik, Ijeoma Opara
JAACAP Open·2026
Objective
Black adolescents differ from adolescents of other racial/ethnic groups in the prevalence, patterns, risk and protective factors, and consequences of substance use, underscoring the need for culturally tailored interventions. Black adolescents also experience unique barriers in access to interventions that may be amenable to digital interventions. However, to our knowledge, no systematic review has examined the efficacy of culturally tailored digital interventions for substance use prevention among Black adolescents. We systematically reviewed existing culturally tailored digital interventions for substance use prevention among Black adolescents and examined their efficacy in preventing substance use.
Method
The authors conducted a systematic search of MEDLINE, Embase, PsycInfo, Cochrane, and Web of Science. Search terms included both controlled vocabulary terms and free text terms for the concepts of digital interventions, substance use, and clinical trials. We included randomized controlled trials comparing a culturally tailored intervention for Black adolescents to a control intervention. We determined the level of cultural tailoring (surface vs. deep-level tailoring) and assessed the impact of the interventions on substance use outcomes. We also evaluated the quality of studies using the NIH Quality Assessment Tool for Controlled Intervention Studies. We conducted a narrative synthesis summarizing results by study characteristics, intervention characteristics, and study outcomes/findings.
Results
Eleven manuscripts comprising of six studies testing six interventions (n=6) met the inclusion criteria. Proportion of black adolescents among studies varied from 41% to 100% (n=109-421). Four interventions significantly improved overall substance use outcomes with effect sizes ranging from 0.002-1.5 for alcohol use, 0.11-1.57 for marijuana use, 0.002-0.64 for tobacco use and 0.009-0.35 for other drugs. Five interventions also improved antecedents to substance use (e.g., self-efficacy, intentions to use drugs, parental monitoring). Effects persisted at long-term follow-ups (≥ 12 months) among 75% of interventions that examined these outcomes. Cultural tailoring varied widely among interventions, with four reporting surface-level adaptations, one reporting deep-level adaptations, and one study reporting both surface- and deep-level adaptations. Cultural tailoring largely focused on intervention content, with only two studies describing additional tailoring at the implementation level. One study assessed the impact of cultural tailoring on intervention outcomes. Interventions were tested in various settings, community (n=2), home (n=1), school (n=1), emergency department (n=1), and primary care (n=1); were delivered using a CD-ROM/computer (n=5) or videotape (n=1); and comprised different types of interventions: universal (n=4), selective (n=1), indicated (n=1).
Conclusion
Although the number of available studies is limited, culturally tailored digital interventions appear to be effective at improving substance use outcomes among Black adolescents and have been tested across various settings. However, the impact of cultural tailoring is challenging to isolate, given the wide variability in the description of culturally tailored content, the lack of homogeneity in the study samples, and the lack of evaluation of the effect of cultural tailoring on intervention outcomes. Given rapid advances in digital technologies and the pressing need to curtail the rise in substance use among Black adolescents, designing, testing, and implementing digital interventions that meet the needs of Black adolescents is imperative.