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Your AI Use Is Breaking My Brain

Jason Koebler

404 Media·2026

AI writing is impossible to avoid, is making everything sound the same, and is driving us crazy.

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I Remember America Before the Measles Vaccine - The Atlantic

Fran Moreland Johns

The Atlantic·2026

And I wish Robert F. Kennedy Jr. did too.

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Seven Years of 700 Cholesterol Without Coronary Atherosclerosis: A Lean Mass Hyper-Responder Case Report

Nicholas G. Norwitz, David Feldman, Adrian Soto-Mota

Diseases·2026

Background: While reducing LDL cholesterol (LDL-C) remains central focuses of conventional preventive cardiology, substantial heterogeneity exists in the cardiovascular risk associated with even extreme LDL-C elevations, likely depending heavily on the broader metabolic context. Specifically, the lean mass hyper-responder (LMHR) phenotype—characterized by markedly elevated LDL-C with elevated high-density lipoprotein cholesterol (HDL-C) and low triglycerides in the setting of a ketogenic diet—has recently been described, though its long-term risk profile remains poorly defined. Case Presentation: We describe a male in his 30s without any congenital dyslipidemia who adopted a ketogenic diet for the management of ulcerative colitis and who subsequently exhibited a sixfold increase in LDL-C from a baseline of 95 mg/dL to 574 mg/dL, with total cholesterol of up to 705 mg/dL, HDL-C at 124 mg/dL, and triglycerides at 34 mg/dL. Despite maintaining these extreme lipid levels for nearly seven years, he demonstrated no coronary plaque or stenosis on coronary computed tomography angiography (CCTA; CAD-RADS = 0). Additionally, quantification of coronary plaque as assessed by AI-guided quantified analysis by Heartflow® identified 0 mm3 plaque in any vessels, placing him in the lowest percentile for atherosclerotic plaque. Conclusions: This case represents an extreme and extensively characterized example of the LMHR phenotype and highlights the limitations of extrapolating cardiovascular risk from LDL-C levels alone without consideration of broader patient context and the etiology of hypercholesterolemia. While a single case cannot redefine clinical practice, this well-characterized case is consistent with emergent literature on LMHR, and careful study of such individuals may provide valuable insights into lipid metabolism, atherosclerosis biology, and precision cardiovascular risk assessment.

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I knew my writing students were using AI. Their confessions led to a powerful teaching moment | AI (artificial intelligence) | The Guardian

Guardian staff reporter

the Guardian·2026

The problem wasn’t just the perfectly polished, yet mediocre prose. It’s what’s lost when we surrender the struggle to translate thought into words

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0416 Living in an Ethnic Enclave is Associated with Reduced Risk of Insomnia Among Asian Americans

Sunmin Lee, Brittany Morey, Yuxi Shi, Susan Redline, Suzanne Bertisch, Ichiro Kawachi

SLEEPJ·2026

Abstract Introduction Neighborhood social and socioeconomic contexts have been linked to insomnia, but few studies have examined this association among Asian Americans, especially the role of ethnic enclaves. Methods The cross-sectional study consisted of 256 Chinese-, 256 Korean- and 267 Vietnamese Americans aged 30+ years in Southern California. We assessed neighborhood characteristics (residential segregation, ethnic enclaves, neighborhood socioeconomic status [nSES]) using geocoded data and neighborhood perceptions (safety, friendliness, social cohesion) by survey. Insomnia was measured using the Insomnia Severity Index (ISI), categorized into no clinically significant insomnia (0-7), subthreshold insomnia (8-14), and moderate/severe insomnia (≥15). Multinomial logistic regression was used to examine associations between neighborhood factors and insomnia, adjusting for age, sex, Asian origin, marital status, education, income, employment status, and population density. Results Results 14.8% reported moderate/severe insomnia. Compared to Asian Americans living in neighborhoods with a lower ethnic enclave index score, those with a higher score had 50% lower odds of moderate/severe insomnia (OR= 0.50, 95% CI: 0.31, 0.79) after adjustment. Report of less friendly neighbors was associated with ,higher odds of moderate/severe insomnia (OR=2.27, 95% CI: 1.08, 4.77), and feeling safe in one’s neighborhood ‘all of the time” was marginally associated with 42% lower odds of moderate/severe insomnia compared to feeling safe “none/some of the time” (OR=0.58, 95% CI: 0.31, 1.07, p< 0.1). Contrary to our hypothesis, higher neighborhood social cohesion was positively associated with subthreshold insomnia (OR=1.36, 95% CI 1.11, 1.67), and marginally associated with higher moderate/severe insomnia (OR=1.28, 95% CI: 0.99, 1.65, p< 0.1). This finding could be potentially due to the significant correlation we found between social cohesion and negative social support (r=0.07, p< 0.05). Interaction test results indicate that the association between living in an ethnic enclave and lower odds of moderate/severe insomnia was especially pronounced among individuals with lower educational attainment, and the association between higher social cohesion and higher odds of insomnia was present for Korean and Vietnamese Americans, but not for Chinese Americans. Conclusion Insomnia among Asian Americans appears to reflect a mix of protective effects of living in ethnic enclaves as well as the “dark side’ of social cohesion (negative social support). Support (if any)

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Natural Language Autoencoders Produce Unsupervised Explanations of LLM Activations

Kit Fraser-Taliente, Subhash Kantamneni, Euan Ong*, Dan Mossing, Christina Lu, Paul C. Bogdan Emmanuel Ameisen, James Chen, Dzmitry Kishylau, Adam Pearce, Julius Tarng, Alex Wu, Jeff Wu, Yang Zhang, Daniel M. Ziegler Evan Hubinger, Joshua Batson, Jack Lindsey, Samuel Zimmerman, Samuel Marks

Anthropic·2026

We introduce Natural Language Autoencoders (NLAs), an unsupervised method for generating natural language explanations of LLM activations. An NLA consists of two LLM modules: an activation verbalizer (AV) that maps an activation to a text description and an activation reconstructor (AR) that maps the description back to an activation. We jointly train the AV and AR with reinforcement learning to reconstruct residual stream activations. Although we optimize for activation reconstruction, the resulting NLA explanations read as plausible interpretations of model internals that, according to our quantitative evaluations, grow more informative over training. We apply NLAs to model auditing. During our pre-deployment audit of Claude Opus 4.6, NLAs helped diagnose safety-relevant behaviors and surfaced unverbalized evaluation awareness—cases where Claude believed, but did not say, that it was being evaluated. We present these audit findings as case studies and corroborate them using independent methods. On an automated auditing benchmark requiring end-to-end investigation of an intentionally-misaligned model, NLA-equipped agents outperform baselines and can succeed even without access to the misaligned model’s training data. NLAs offer a convenient interface for interpretability, with expressive natural language explanations that we can directly read. To support further work, we release training code and trained NLAs for popular open models.

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A Scoping Review of Australian Aboriginal Early Relational Health Knowledge Systems

Shannon McNeair, Catherine Chamberlain, Naomi Priest, Tracy Evans-Whipp, Suzanne Vassallo, Kayla Mansour, Lisa Ritland, Craig A. Olsson, Juli Coffin

Clinical Child and Family Psychology Review·2026

Abstract Australian Aboriginal people have evolved advanced relational knowledge systems for raising children and young people over thousands of years. Documentation of this knowledge within peer-reviewed literature is dispersed across a broad set of disciplines and sources that are mostly contextualised within Eurocentric frameworks. In this scoping review, we describe the literature on Australian Aboriginal Early Relational Knowledge Systems. Our aim is to describe how Australian Aboriginal approaches to relational wellbeing uniquely promote health and human development from pre-conception, to childhood, to adolescence and into parenting next generation offspring. We privilege Australian Indigenous authors as the holders of knowledge and limit our review to data sources led by Australian Indigenous people. A systematic search for relevant studies was conducted across four databases: MEDLINE, PsycINFO, Embase and CINAHL. This yielded 5,141 articles, of which 26 met criteria. A further 5 articles were identified through citation searching resulting in 31 included articles. We describe how Aboriginal children and young people develop relational security through engagement with multiple complex social systems within family and community, through interaction with Country, and across human and non-human elements, many features of which are missed in Western theories and Western interpretation of Aboriginal relational knowledge. Culturally valid and reliable assessment measures are urgently needed to accurately represent and monitor population relational health in Aboriginal children and young people.

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Minority Stress as a Risk Factor for Depression Symptoms and Sleep Disturbance among Sexual Minority Individuals: The Role of Cognitive and Emotional Dysregulation

Randolph C. H. Chan, Yiu Tung Suen, Eliz Miu Yin Wong

Sexuality Research and Social Policy·2026

Abstract Introduction Although recent research indicates that sexual minority individuals are at greater risk of sleep disturbance compared to their heterosexual counterparts, the mechanisms underlying these disparities remain poorly understood. This study examines the relationships between minority stress, cognitive and emotional dysregulation, and sleep disturbance among sexual minority individuals. Methods A total of 1,457 sexual minority individuals were involved in the study. They completed a questionnaire assessing minority stress, cognitive and emotional dysregulation, depression symptoms, and sleep disturbance. Results Heterosexist discrimination and internalized heterosexism were positively associated with sleep disturbance. Heterosexist discrimination was linked to rumination and catastrophizing, which in turn were associated with depression symptoms and sleep disturbance. Similarly, internalized heterosexism showed significant indirect associations with sleep disturbance via rumination, catastrophizing, and depression symptoms. Additionally, bisexual and pansexual individuals exhibited greater vulnerability to sleep disturbance and stronger associations between heterosexist discrimination and sleep disturbance compared to gay men and lesbian women. Conclusions This study emphasizes the need to address minority stress as a significant determinant of sleep disturbance among sexual minority individuals. Policy Implications The findings have important implications for cognitive-behavioral interventions and sleep hygiene education tailored to sexual minority individuals experiencing sleep difficulties.

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All Papers

Your AI Use Is Breaking My Brain

I Remember America Before the Measles Vaccine - The Atlantic

Seven Years of 700 Cholesterol Without Coronary Atherosclerosis: A Lean Mass Hyper-Responder Case Report

I knew my writing students were using AI. Their confessions led to a powerful teaching moment | AI (artificial intelligence) | The Guardian

0416 Living in an Ethnic Enclave is Associated with Reduced Risk of Insomnia Among Asian Americans

Natural Language Autoencoders Produce Unsupervised Explanations of LLM Activations

Beyond P(doom) for AI Risk: Quantifying Uncertainty Without Probability | Center for Security and Emerging Technology

What Makes Art Great? - Nabeel S. Qureshi

A Scoping Review of Australian Aboriginal Early Relational Health Knowledge Systems

Examining the relationship between racism-related stress and coping among Black adolescents

Minority Stress as a Risk Factor for Depression Symptoms and Sleep Disturbance among Sexual Minority Individuals: The Role of Cognitive and Emotional Dysregulation

Painful hopes? The health and well-being impacts of land expropriation in Chinese villages