Newest Papers
Cueva del Arco: Paleoecological insights into Paleolithic landscapes
José S. Carrión, Yolanda Carrión-Marco, Carmen M. Martínez-Varea, Juan Ochando, Cristina Real-Margalef, Manuel Munuera, Gloria Martínez-Sagarra, Gabriela Amorós, Aldara Girona, Diego Angelucci, Jacopo Armellini, Noelia Sánchez-Martínez, Dídac Román, Ignacio Martín-Lerma
Quaternary Science Advances·2025
This article presents new data from Cueva del Arco and offers a comprehensive perspective on the palae- oenvironments inhabited by Neanderthals and Homo sapiens in the interior of Murcia, southeastern Spain, during the Mousterian and Gravettian periods. We focus on the ecological structure and floristic composition of pre- historic landscapes, drawing on pollen records from coprolites and cave sediments, as well as charcoal and plant macroremains, particularly seeds. Vertebrate assemblages are discussed through taphonomic and paleoecological lenses. Our results show that the landscapes surrounding Cueva del Arco during MIS 3 underwent only limited changes despite climatic fluctuations, likely buffered by nearby glacial strongholds, such as immediate riverine hydrorefugia and biodiversity reservoirs in the Segura-Cazorla-Alcaraz Mountains. We highlight the coexistence of plant species with currently disparate bioclimatic affinities, suggesting a compression of vegetation belts. Locally, under the edaphic influence of lithosols overlying karstic bedrock, the landscape remained open, with scattered trees or small groves on deeper soils. Notably, Cupressaceae were a dominant feature of the local vegetation and constituted a critical resource for firewood, supporting human adaptation to the environment. In this resilient and ecologically diverse setting, Paleolithic populations had access to a wide variety of plant and animal resources essential for their survival.
No ratings yet
View paper →62654 Trichoscopic Patterns of Frontal Fibrosing Alopecia: A Systematic Review and Prevalence Meta-Analysis
Lyria de Oliveira Rosa, Fabiana Castro Porto Silva Lopes, Beatriz Ximenes Mendes, Deivyd Vieira Silva Cavalcante, Michele Kreuz, Sarah Soares Amorim, Lilia Maria Lima de Oliveira
Journal of the American Academy of Dermatology·2025
No abstract available
★ 5.0 (1)
View paper →64415 Early Emollients Use to Prevent Atopic Dermatitis in Infants: A Systematic Review and Meta-Analysis
Isabelle Reis, Nathália Borba, Gabrielle Henrique, Lyria Rosa, Maria Fernanda Severo, Rayane Sales, Ana Luiza Gonçalves, Blanca Dantas, Lilia Oliveira
Journal of the American Academy of Dermatology·2025
No abstract available
★ 5.0 (1)
View paper →60716 Cutaneous Manifestations in Acromegaly: A Systematic Review and Meta-Analysis
Lilia Maria Lima de Oliveira, Deivyd Vieira Silva Cavalcante, Beatriz Ximenes Mendes, Lyria de Oliveira Rosa, Sarah Soares Amorim, Fabiana Castro Porto Silva Lopes, Michele Kreuz
Journal of the American Academy of Dermatology·2025
No abstract available
★ 5.0 (1)
View paper →62471 Topical Finasteride Combined with Minoxidil for Androgenetic Alopecia: An Updated Systematic Review and Meta-analysis
Carolina Mira Dilly de Medeiros, Ana Carolina Putini Vieira, Ana Carolina Ventura de Santana de Jesus, Isabelle Albuquerque Reis, Letícia Hanna Moura da Silva Gattas Graciolli, Yasmin da Silva Moura, Beatriz Ximenes Mendes, Anelise Poluboiarinov Cappellaro, Lyria de Oliveira Rosa, Ana Carolina Seiler Mendes
Journal of the American Academy of Dermatology·2025
No abstract available
★ 5.0 (1)
View paper →62527 Efficacy of liposomal amphotericin b for treating persistent post-kala-azar dermal leishmaniasis: a systematic review and pooled analysis of randomized controlled trials
Deivyd Cavalcante, Lilia Maria Oliveira, Fernanda Zamora, Beatriz Mendes, Nicole Pimenta, Lyria Rosa, Michele Kreuz, Andres Villca Zamora, Sarah Amorin, Gabriel Lopes, Fabiana Silva Lopes
Journal of the American Academy of Dermatology·2025
No abstract available
★ 5.0 (1)
View paper →60217 Paradoxical Eczema Prevalence in Patients Treated with Biologics for Psoriasis: A Systematic Review and Meta-analysis
Deivyd Cavalcante, Lilia Maria de Oliveira, Beatriz Mendes, Sarah Amorim, Michele Kreuz, Lyria Rosa, Fabiana Lopes
Journal of the American Academy of Dermatology·2025
No abstract available
★ 5.0 (1)
View paper →64138 Association between Alopecia Areata and Psychiatric Disorders: A Systematic Review and Meta-analysis
Nathália Borba, Lyria Rosa, Gabrielle Henrique, Isabelle Reis, Rayane Sales, Blanca Dantas, Júlia Gadelha, Karolina Amorim, Arthur Petrucci, Thais Pincelli
Journal of the American Academy of Dermatology·2025
No abstract available
★ 5.0 (1)
View paper →64082 Combined Minoxidil and Platelet-Rich Plasma Compared With Monotherapy in Androgenetic Alopecia: A Systematic Review and Meta-analysis of Randomized Controlled Trials
Nathália Borba, Isabelle Reis, Rayane Sales, Beatriz Mendes, Gabrielle Henrique, Lyria Rosa, Raphael Brito, Thais Pincelli
Journal of the American Academy of Dermatology·2025
No abstract available
★ 5.0 (1)
View paper →64203 Association between Atopic Dermatitis and Electronic Cigarette Smoking: a Systematic Review and Meta-analysis
Sarah Soares Amorim, Fabiana Castro Porto Silva Lopes, Beatriz Ximenes Mendes, Deivyd Vieira Silva Cavalcante, Michele Kreuz, Lyria de Oliveira Rosa, Lilia Maria Lima de Oliveira
Journal of the American Academy of Dermatology·2025
No abstract available
★ 5.0 (1)
View paper →Machine learning-enabled detection of electrophysiological signatures in iPSC-derived models of schizophrenia and bipolar disorder
Kai Cheng, Autumn Williams, Anannya Kshirsagar, Sai Kulkarni, Rakesh Karmacharya, Deok-Ho Kim, Sridevi V. Sarma, Annie Kathuria
APL Bioengineering·2025
<jats:p>Neuropsychiatric disorders such as schizophrenia (SCZ) and bipolar disorder (BD) remain challenging to diagnose due to the absence of objective biomarkers, with current assessments relying largely on subjective clinical evaluations. In this study, we present a computational analysis pipeline designed to identify disease-specific electrophysiological signatures from multi-electrode array (MEA) recordings of patient-derived cerebral organoids (COs) and two-dimensional cortical interneuron cultures (2DNs). Using a Support Vector Machine classifier optimized for high-dimensional data, we achieved 95.8% classification accuracy in distinguishing SCZ from control samples in 2DNs under both baseline and post-electrical-stimulation (PES) conditions with the extracted electrophysiological signatures. In COs, classification accuracy improved from 83.3% at baseline to 91.6% following PES, enabling robust separation of control, SCZ, and BD cohorts. Key discriminative features included channel-specific measures of network activity, with PES significantly enhancing classification performance, particularly for BD. These results underscore the potential of MEA-based functional phenotyping, coupled with machine learning, to uncover reliable, stimulation-sensitive electrophysiological biomarkers, offering a path toward more objective diagnosis and personalized treatment strategies for neuropsychiatric disorders.</jats:p>
No ratings yet
View paper →Learning to Love Rats: A Postwar Ecology in a Cambodian Minefield
Darcie DeAngelo
American Anthropologist·2025
<jats:title>ABSTRACT</jats:title>
<jats:p>This paper follows the implementation of landmine detection rats in Cambodia. Over the course of my ethnographic fieldwork with the team for the landmine detection rat technique training in Cambodia, I saw that the way the human landmine detectors (a.k.a. deminers) learned to love the rats also changed how they also learned to live and work with each other. Deminers themselves were usually former soldiers, many of whom had fought on opposite sides during Cambodia's civil wars. Their labor in the minefield was inherently aspirational, and rats were employed in this future imaginary. They worked with former soldiers who, as Theravada Buddhists, would sometimes use the religious word “metta” for the love they felt for their rats, which they defined as “pity‐love.” Metta is a love, I was told, “that can make a cruel person kind.” This expression had a particular valence for deminers who had to work with former combatants, where the stigma of past violence made it uncomfortable to directly address such former enmities. Loving the rats sublimated the minefield's potential violence into potential pity‐love for and with colleagues, mediating a violent past to work together toward a previously unimaginable future: a postwar ecology.</jats:p>
No ratings yet
View paper →