Lipotoxicity Causes Multisystem Organ Failure and Exacerbates Acute Pancreatitis in Obesity

Sarah Navina, Chathur Acharya, James P. DeLany, Lidiya S. Orlichenko, Catherine J. Baty, Sruti S. Shiva, Chandra Durgampudi, Jenny M. Karlsson, Kenneth Lee, Kyongtae T. Bae, Alessandro Furlan, Jaideep Behari, Shiguang Liu, Teresa McHale, Larry Nichols, Georgios Ioannis Papachristou, Dhiraj Yadav, Vijay P. Singh

Science Translational Medicine11/2/2011·DOI·Read paper

Abstract

Unsaturated fatty acids cause lipotoxicity and mediate acute adverse outcomes in obese individuals with pancreatitis.

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